Photodynamic therapy: treatment of skin diseases and tumors

One of the most effective modern methods to fight skin diseases and cancer pathologies experts believe photodynamic therapy – a method based on the ability of light particles (photons) to initiate the development of specific reactions. Today this method is actively used even in the treatment of weak and elderly patients.

What is its essence?

Photodynamic therapy conditionally can be divided into two stages.

The first step is taking the drug, can accumulate on the membranes or within pathologically altered cells and to increase their sensitivity to the light beams. Drugs can be administered intravenously, be in the form of tablets or capsules, or applied to the affected area of tissue.

The second stage is the impact on the patient’s body (or specific area) of the light beam (laser). The depth and duration of exposure are determined individually.

Under the action of a laser at diseased cells start to occur chemical reaction in the process which are toxic, corrosive substances. These substances cause cell death, and tumor or element skin disease dies. While healthy tissue remains intact, and the patient caused minimal damage.

In some cases, it can be used?

The indications for the use of photodynamic therapy can include:

  • tumors that are not amenable to other therapies (particularly malignant neoplasms of skin – basal cell and squamous cell carcinoma);
  • the recurrence of an oncological pathology;
  • cancer, if you cannot use other methods due to the advanced age of the patient or the existence of severe comorbidities;
  • dermatoses that are resistant to traditional methods of treatment;
  • often recurrent dermatosis;
  • skin disease with large lesions of the skin;
  • vulgar warts and giant condyloma;
  • hypertrichosis;
  • female alopecia;
  • keloid scars;
  • scleroderma;
  • acne;
  • psoriasis;
  • actinic cheilitis;
  • erythroplasia;
  • keratoakantoma;
  • Kaposi’s sarcoma and other tumors.

Relative contraindication to its use is the presence of allergic disease and distant or regional metastases of tumors. Absolute contraindications are: heart and lung failure, severe liver disease and kidney failure, systemic lupus erythematosus, and of extreme exhaustion of the patient.

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